Empirical Analysis of Digital Gene Expression Data in R


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Documentation for package ‘edgeR’ version 3.30.0

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A B C D E F G H K L M N O P Q R S T V W Z misc

edgeR-package Empirical analysis of digital gene expression data in R

-- A --

addPriorCount Add a prior count
adjustedProfileLik Adjusted Profile Likelihood for the Negative Binomial Dispersion Parameter
as.data.frame.DGEExact Turn a TopTags Object into a Dataframe
as.data.frame.DGELRT Turn a TopTags Object into a Dataframe
as.data.frame.TopTags Turn a TopTags Object into a Dataframe
as.matrix.CompressedMatrix makeCompressedMatrix
as.matrix.DGEList Turn a DGEList Object into a Matrix
aveLogCPM Average Log Counts Per Million
aveLogCPM.default Average Log Counts Per Million
aveLogCPM.DGEGLM Average Log Counts Per Million
aveLogCPM.DGEList Average Log Counts Per Million
aveLogCPM.SummarizedExperiment Average Log Counts Per Million

-- B --

binMeanVar Explore the Mean-Variance Relationship for DGE Data
binomTest Exact Binomial Tests for Comparing Two Digital Libraries

-- C --

calcNormFactors Calculate Normalization Factors to Align Columns of a Count Matrix
calcNormFactors.default Calculate Normalization Factors to Align Columns of a Count Matrix
calcNormFactors.DGEList Calculate Normalization Factors to Align Columns of a Count Matrix
calcNormFactors.SummarizedExperiment Calculate Normalization Factors to Align Columns of a Count Matrix
calcNormOffsetsforChIP Normalize ChIP-Seq Read Counts to Input and Test for Enrichment
camera.DGEList Competitive Gene Set Tests for Digital Gene Expression Data
catchKallisto Process Kallisto or Salmon Output
catchSalmon Process Kallisto or Salmon Output
cbind Combine DGEList Objects
cbind.CompressedMatrix makeCompressedMatrix
cbind.DGEList Combine DGEList Objects
commonCondLogLikDerDelta Conditional Log-Likelihoods in Terms of Delta
CompressedMatrix makeCompressedMatrix
CompressedMatrix-class makeCompressedMatrix
condLogLikDerDelta Conditional Log-Likelihood of the Dispersion for a Single Group of Replicate Libraries
condLogLikDerSize Conditional Log-Likelihood of the Dispersion for a Single Group of Replicate Libraries
cpm Counts per Million or Reads per Kilobase per Million
cpm.default Counts per Million or Reads per Kilobase per Million
cpm.DGEGLM Counts per Million or Reads per Kilobase per Million
cpm.DGEList Counts per Million or Reads per Kilobase per Million
cpm.DGELRT Counts per Million or Reads per Kilobase per Million
cpm.SummarizedExperiment Counts per Million or Reads per Kilobase per Million
cpmByGroup Counts per Million or Reads per Kilobase per Million
cpmByGroup.default Counts per Million or Reads per Kilobase per Million
cpmByGroup.DGEList Counts per Million or Reads per Kilobase per Million
cpmByGroup.SummarizedExperiment Counts per Million or Reads per Kilobase per Million
cutWithMinN Cut numeric vector into non-empty intervals

-- D --

decideTests.DGEExact Multiple Testing Across Genes and Contrasts
decideTests.DGELRT Multiple Testing Across Genes and Contrasts
decideTestsDGE Multiple Testing Across Genes and Contrasts
designAsFactor Fit Negative Binomial Generalized Linear Models to Multiple Response Vectors: Low Level Functions
DGEExact-class differential expression of Digital Gene Expression data - class
DGEGLM-class Digital Gene Expression Generalized Linear Model results - class
DGEList DGEList Constructor
DGEList-class Digital Gene Expression data - class
DGELRT-class Digital Gene Expression Likelihood Ratio Test data and results - class
diffSpliceDGE Test for Differential Exon Usage
dim.CompressedMatrix makeCompressedMatrix
dim.DGEExact Retrieve the Dimensions of a DGEList, DGEExact, DGEGLM, DGELRT or TopTags Object
dim.DGEGLM Retrieve the Dimensions of a DGEList, DGEExact, DGEGLM, DGELRT or TopTags Object
dim.DGEList Retrieve the Dimensions of a DGEList, DGEExact, DGEGLM, DGELRT or TopTags Object
dim.DGELRT Retrieve the Dimensions of a DGEList, DGEExact, DGEGLM, DGELRT or TopTags Object
dim.TopTags Retrieve the Dimensions of a DGEList, DGEExact, DGEGLM, DGELRT or TopTags Object
dimnames.DGEExact Retrieve the Dimension Names of a DGE Object
dimnames.DGEGLM Retrieve the Dimension Names of a DGE Object
dimnames.DGEList Retrieve the Dimension Names of a DGE Object
dimnames.DGELRT Retrieve the Dimension Names of a DGE Object
dimnames.TopTags Retrieve the Dimension Names of a DGE Object
dimnames<-.DGEExact Retrieve the Dimension Names of a DGE Object
dimnames<-.DGEGLM Retrieve the Dimension Names of a DGE Object
dimnames<-.DGEList Retrieve the Dimension Names of a DGE Object
dimnames<-.DGELRT Retrieve the Dimension Names of a DGE Object
dispBinTrend Estimate Dispersion Trend by Binning for NB GLMs
dispCoxReid Estimate Common Dispersion for Negative Binomial GLMs
dispCoxReidInterpolateTagwise Estimate Genewise Dispersion for Negative Binomial GLMs by Cox-Reid Adjusted Profile Likelihood
dispCoxReidPowerTrend Estimate Dispersion Trend for Negative Binomial GLMs
dispCoxReidSplineTrend Estimate Dispersion Trend for Negative Binomial GLMs
dispDeviance Estimate Common Dispersion for Negative Binomial GLMs
dispPearson Estimate Common Dispersion for Negative Binomial GLMs
dropEmptyLevels Drop Levels of a Factor that Never Occur

-- E --

edgeR Empirical analysis of digital gene expression data in R
edgeRUsersGuide View edgeR User's Guide
effectiveLibSizes Effective Library Sizes
effectiveLibSizes.default Effective Library Sizes
effectiveLibSizes.DGEGLM Effective Library Sizes
effectiveLibSizes.DGEList Effective Library Sizes
effectiveLibSizes.DGELRT Effective Library Sizes
equalizeLibSizes Equalize Library Sizes by Quantile-to-Quantile Normalization
equalizeLibSizes.default Equalize Library Sizes by Quantile-to-Quantile Normalization
equalizeLibSizes.DGEList Equalize Library Sizes by Quantile-to-Quantile Normalization
estimateCommonDisp Estimate Common Negative Binomial Dispersion by Conditional Maximum Likelihood
estimateCommonDisp.default Estimate Common Negative Binomial Dispersion by Conditional Maximum Likelihood
estimateCommonDisp.DGEList Estimate Common Negative Binomial Dispersion by Conditional Maximum Likelihood
estimateDisp Estimate Common, Trended and Tagwise Negative Binomial dispersions by weighted likelihood empirical Bayes
estimateDisp.default Estimate Common, Trended and Tagwise Negative Binomial dispersions by weighted likelihood empirical Bayes
estimateDisp.DGEList Estimate Common, Trended and Tagwise Negative Binomial dispersions by weighted likelihood empirical Bayes
estimateDisp.SummarizedExperiment Estimate Common, Trended and Tagwise Negative Binomial dispersions by weighted likelihood empirical Bayes
estimateExonGenewiseDisp Estimate Genewise Dispersions from Exon-Level Count Data
estimateGLMCommonDisp Estimate Common Dispersion for Negative Binomial GLMs
estimateGLMCommonDisp.default Estimate Common Dispersion for Negative Binomial GLMs
estimateGLMCommonDisp.DGEList Estimate Common Dispersion for Negative Binomial GLMs
estimateGLMRobustDisp Empirical Robust Bayes Tagwise Dispersions for Negative Binomial GLMs using Observation Weights
estimateGLMTagwiseDisp Empirical Bayes Tagwise Dispersions for Negative Binomial GLMs
estimateGLMTagwiseDisp.default Empirical Bayes Tagwise Dispersions for Negative Binomial GLMs
estimateGLMTagwiseDisp.DGEList Empirical Bayes Tagwise Dispersions for Negative Binomial GLMs
estimateGLMTrendedDisp Estimate Trended Dispersion for Negative Binomial GLMs
estimateGLMTrendedDisp.default Estimate Trended Dispersion for Negative Binomial GLMs
estimateGLMTrendedDisp.DGEList Estimate Trended Dispersion for Negative Binomial GLMs
estimateTagwiseDisp Estimate Empirical Bayes Tagwise Dispersion Values
estimateTagwiseDisp.default Estimate Empirical Bayes Tagwise Dispersion Values
estimateTagwiseDisp.DGEList Estimate Empirical Bayes Tagwise Dispersion Values
estimateTrendedDisp Estimate Empirical Bayes Trended Dispersion Values
estimateTrendedDisp.default Estimate Empirical Bayes Trended Dispersion Values
estimateTrendedDisp.DGEList Estimate Empirical Bayes Trended Dispersion Values
exactTest Exact Tests for Differences between Two Groups of Negative-Binomial Counts
exactTestBetaApprox Exact Tests for Differences between Two Groups of Negative-Binomial Counts
exactTestByDeviance Exact Tests for Differences between Two Groups of Negative-Binomial Counts
exactTestBySmallP Exact Tests for Differences between Two Groups of Negative-Binomial Counts
exactTestDoubleTail Exact Tests for Differences between Two Groups of Negative-Binomial Counts
expandAsMatrix expandAsMatrix

-- F --

filterByExpr Filter Genes By Expression Level
filterByExpr.default Filter Genes By Expression Level
filterByExpr.DGEList Filter Genes By Expression Level
filterByExpr.SummarizedExperiment Filter Genes By Expression Level
fry.DGEList Self-contained Gene Set Tests for Digital Gene Expression Data

-- G --

getCounts Extract Specified Component of a DGEList Object
getDispersion Extract Specified Component of a DGEList Object
getOffset Extract Specified Component of a DGEList Object
getPriorN Get a Recommended Value for Prior N from DGEList Object
gini Gini dispersion index
glmFit Genewise Negative Binomial Generalized Linear Models
glmFit.default Genewise Negative Binomial Generalized Linear Models
glmFit.DGEList Genewise Negative Binomial Generalized Linear Models
glmFit.SummarizedExperiment Genewise Negative Binomial Generalized Linear Models
glmLRT Genewise Negative Binomial Generalized Linear Models
glmQLFit Genewise Negative Binomial Generalized Linear Models with Quasi-likelihood Tests
glmQLFit.default Genewise Negative Binomial Generalized Linear Models with Quasi-likelihood Tests
glmQLFit.DGEList Genewise Negative Binomial Generalized Linear Models with Quasi-likelihood Tests
glmQLFit.SummarizedExperiment Genewise Negative Binomial Generalized Linear Models with Quasi-likelihood Tests
glmQLFTest Genewise Negative Binomial Generalized Linear Models with Quasi-likelihood Tests
glmTreat Test for Differential Expression Relative to a Threshold
goana.DGEExact Gene Ontology or KEGG Analysis of Differentially Expressed Genes
goana.DGELRT Gene Ontology or KEGG Analysis of Differentially Expressed Genes
gof Goodness of Fit Tests for Multiple GLM Fits
goodTuring Good-Turing Frequency Estimation
goodTuringPlot Good-Turing Frequency Estimation
goodTuringProportions Good-Turing Frequency Estimation

-- H --

head.DGEExact Return the First to Last Part of a Data Object
head.DGEGLM Return the First to Last Part of a Data Object
head.DGEList Return the First to Last Part of a Data Object
head.DGELRT Return the First to Last Part of a Data Object
head.TopTags Return the First to Last Part of a Data Object

-- K --

kegga.DGEExact Gene Ontology or KEGG Analysis of Differentially Expressed Genes
kegga.DGELRT Gene Ontology or KEGG Analysis of Differentially Expressed Genes

-- L --

length.CompressedMatrix makeCompressedMatrix
locfitByCol Locally Weighted Mean By Column
loessByCol Locally Weighted Mean By Column

-- M --

makeCompressedMatrix makeCompressedMatrix
maPlot Plots Log-Fold Change versus Log-Concentration (or, M versus A) for Count Data
maximizeInterpolant Maximize a function given a table of values by spline interpolation.
maximizeQuadratic Maximize a function given a table of values by quadratic interpolation.
mglm Fit Negative Binomial Generalized Linear Models to Multiple Response Vectors: Low Level Functions
mglmLevenberg Fit Negative Binomial Generalized Linear Models to Multiple Response Vectors: Low Level Functions
mglmOneGroup Fit Negative Binomial Generalized Linear Models to Multiple Response Vectors: Low Level Functions
mglmOneWay Fit Negative Binomial Generalized Linear Models to Multiple Response Vectors: Low Level Functions
modelMatrixMeth Construct Design Matrix for edgeR Analysis of Methylation Count Data
movingAverageByCol Moving Average Smoother of Matrix Columns
mroast.DGEList Self-contained Gene Set Tests for Digital Gene Expression Data

-- N --

nbinomDeviance Negative Binomial Deviance
nbinomUnitDeviance Negative Binomial Unit Deviance
nearestReftoX Find Nearest Element of Reference for each Element of X
nearestTSS Find Nearest Transcriptional Start Site
normalizeChIPtoInput Normalize ChIP-Seq Read Counts to Input and Test for Enrichment

-- O --

Ops.CompressedMatrix makeCompressedMatrix

-- P --

plotBCV Plot Biological Coefficient of Variation
plotExonUsage Create a Plot of Exon Usage from Exon-Level Count Data
plotMD.DGEExact Mean-Difference Plot of Count Data
plotMD.DGEGLM Mean-Difference Plot of Count Data
plotMD.DGEList Mean-Difference Plot of Count Data
plotMD.DGELRT Mean-Difference Plot of Count Data
plotMD.SummarizedExperiment Mean-Difference Plot of Count Data
plotMDS.DGEList Multidimensional scaling plot of distances between digital gene expression profiles
plotMDS.SummarizedExperiment Multidimensional scaling plot of distances between digital gene expression profiles
plotMeanVar Explore the Mean-Variance Relationship for DGE Data
plotMeanVar2 Plot Mean-Variance Relationship in DGE Data Using Standardized Residuals
plotQLDisp Plot the quasi-likelihood dispersion
plotSmear Smear plot
plotSpliceDGE Differential splicing plot
predFC Predictive log-fold changes
predFC.default Predictive log-fold changes
predFC.DGEList Predictive log-fold changes
predFC.SummarizedExperiment Predictive log-fold changes
processAmplicons Process raw data from pooled genetic sequencing screens

-- Q --

q2qnbinom Quantile to Quantile Mapping between Negative-Binomial Distributions
q2qpois Quantile to Quantile Mapping between Negative-Binomial Distributions

-- R --

rbind.CompressedMatrix makeCompressedMatrix
rbind.DGEList Combine DGEList Objects
read10X Read 10X Genomics Files
readBismark2DGE Read Bismark Coverage Files
readDGE Read and Merge a Set of Files Containing Count Data
roast.DGEList Self-contained Gene Set Tests for Digital Gene Expression Data
romer.DGEList Rotation Gene Set Enrichment for Digital Gene Expression Data
rowsum.DGEList Sum Over Groups of Genes
rowsum.SummarizedExperiment Sum Over Groups of Genes
rpkm Counts per Million or Reads per Kilobase per Million
rpkm.default Counts per Million or Reads per Kilobase per Million
rpkm.DGEGLM Counts per Million or Reads per Kilobase per Million
rpkm.DGEList Counts per Million or Reads per Kilobase per Million
rpkm.DGELRT Counts per Million or Reads per Kilobase per Million
rpkm.SummarizedExperiment Counts per Million or Reads per Kilobase per Million
rpkmByGroup Counts per Million or Reads per Kilobase per Million
rpkmByGroup.default Counts per Million or Reads per Kilobase per Million
rpkmByGroup.DGEList Counts per Million or Reads per Kilobase per Million
rpkmByGroup.SummarizedExperiment Counts per Million or Reads per Kilobase per Million

-- S --

scaleOffset Scale offsets
scaleOffset.default Scale offsets
scaleOffset.DGEList Scale offsets
SE2DGEList SummarizedExperiment to DGEList
show-method differential expression of Digital Gene Expression data - class
show-method Digital Gene Expression Generalized Linear Model results - class
show-method Digital Gene Expression Likelihood Ratio Test data and results - class
show-method Table of the Top Differentially Expressed Genes/Tags
spliceVariants Identify Genes with Splice Variants
splitIntoGroups Split the Counts or Pseudocounts from a DGEList Object According To Group
splitIntoGroups.default Split the Counts or Pseudocounts from a DGEList Object According To Group
splitIntoGroups.DGEList Split the Counts or Pseudocounts from a DGEList Object According To Group
splitIntoGroupsPseudo Split the Counts or Pseudocounts from a DGEList Object According To Group
subsetting Subset DGEList, DGEGLM, DGEExact and DGELRT Objects
sumTechReps Sum Over Replicate Samples
sumTechReps.default Sum Over Replicate Samples
sumTechReps.DGEList Sum Over Replicate Samples
sumTechReps.SummarizedExperiment Sum Over Replicate Samples
systematicSubset Take a systematic subset of indices.

-- T --

tail.DGEExact Return the First to Last Part of a Data Object
tail.DGEGLM Return the First to Last Part of a Data Object
tail.DGEList Return the First to Last Part of a Data Object
tail.DGELRT Return the First to Last Part of a Data Object
tail.TopTags Return the First to Last Part of a Data Object
thinCounts Binomial or Multinomial Thinning of Counts
topSpliceDGE Top table of differentially spliced genes or exons
topTags Table of the Top Differentially Expressed Genes/Tags
TopTags-class Table of the Top Differentially Expressed Genes/Tags

-- V --

validDGEList Check for Valid DGEList object
voomLmFit Apply voom-lmFit Pipeline While Accounting for Loss of Residual DF Due to Exact Zeros

-- W --

weightedCondLogLikDerDelta Weighted Conditional Log-Likelihood in Terms of Delta
WLEB Weighted Likelihood Empirical Bayes

-- Z --

zscoreNBinom Z-score Equivalents of Negative Binomial Deviate

-- misc --

[.CompressedMatrix makeCompressedMatrix
[.DGEExact Subset DGEList, DGEGLM, DGEExact and DGELRT Objects
[.DGEGLM Subset DGEList, DGEGLM, DGEExact and DGELRT Objects
[.DGEList Subset DGEList, DGEGLM, DGEExact and DGELRT Objects
[.DGELRT Subset DGEList, DGEGLM, DGEExact and DGELRT Objects
[.TopTags Subset DGEList, DGEGLM, DGEExact and DGELRT Objects
[<-.CompressedMatrix makeCompressedMatrix